Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414244 | 0.81 | RXRA (0.44) | PPARGPPARA | |
| SCHEMBL8414269 | 0.76 | PPARG (0.32) | PPARGPPARA | |
| SCHEMBL8414339 | 0.76 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL8414455 | 0.72 | CPB2 (0.35) | PPARGPPARA | |
| SCHEMBL8412747 | 0.71 | PPARG (0.33) | PPARGPPARA | |
| SCHEMBL8414351 | 0.70 | PTGIR (0.30) | — | |
| SCHEMBL8410905 | 0.69 | PTGIR (0.49) | — | |
| Histidine SCHEMBL27973988 | 0.66 | CYP1A2 (0.38) | — | |
| Histidine SCHEMBL28683627 | 0.66 | SLC7A5 (0.45) | — | |
| SCHEMBL7433498 | 0.64 | PTPRA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |