Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409654 | 0.84 | POLB (0.48) | KMT2AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16891423 | 0.80 | HSD17B3 (0.53) | KMT2AHPGDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1680458 | 0.79 | CA12 (0.55) | KMT2AMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL10749473 | 0.77 | KMT2A (0.61) | KMT2AMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL8619424 | 0.77 | NR4A2 (0.52) | KMT2AHPGDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1374042 | 0.76 | HSD17B3 (0.61) | KMT2AMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL6650021 | 0.74 | LMNA (0.61) | KMT2AMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL4686898 | 0.74 | LMNA (0.61) | KMT2AMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL10456907 | 0.74 | KMT2A (0.68) | KMT2AMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL10596300 | 0.74 | KMT2A (0.65) | KMT2AMAPTHPGDALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994540-A | HYDROXY- AND CHLORO-PYRIDYLPYRIDAZINONE DERIVATIVES | LONZA, LTD. (CH) | 1999-11-30 | — | — | US | disclosed |