Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413669 | 0.91 | ACHE (0.47) | ACHEAGTR1AGTR2LTB4R2 | |
| SCHEMBL7847610 | 0.91 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8502142 | 0.89 | ACHE (0.54) | ACHEAGTR1AGTR2LTB4R2 | |
| SCHEMBL8323609 | 0.86 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8678184 | 0.84 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7850545 | 0.82 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL7849540 | 0.79 | AGTR1 (0.56) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8411067 | 0.79 | AGTR1 (0.54) | ACHEAGTR1AGTR2LTB4R2 | |
| SCHEMBL8675328 | 0.78 | TSHR (0.34) | ACHEAGTR1AGTR2 | |
| SCHEMBL8414576 | 0.76 | AGTR1 (0.51) | ACHEAGTR1AGTR2LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004979-A | ANGIOTENSIN II INHIBITORS; 4-((CARBOXY)ARYLOXY)-QUINOLINE DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1999-12-21 | — | — | US | disclosed |
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |
| US-5817674-A | ANTIOTENSIN II RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1998-10-06 | — | — | US | disclosed |