Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413083 | 0.78 | ACHE (0.47) | ACHEAGTR1AGTR2 | |
| SCHEMBL8413669 | 0.70 | ACHE (0.47) | ACHEAGTR1AGTR2 | |
| SCHEMBL8525724 | 0.69 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8678184 | 0.68 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8502142 | 0.68 | ACHE (0.54) | ACHEAGTR1AGTR2 | |
| SCHEMBL8323609 | 0.66 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7134084 | 0.62 | PTPN11 (0.44) | TSHRLMNAALDH1A1ACHEAGTR1 | |
| SCHEMBL8674166 | 0.62 | PLA2G2A (0.44) | ALDH1A1ACHEAGTR1AGTR2MAPT | |
| SCHEMBL9531774 | 0.61 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL1789262 | 0.61 | ALDH1A1 (0.66) | TSHRLMNAALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817674-A | ANTIOTENSIN II RECEPTOR ANTAGONISTS | ROUSSEL UCLAF (FR) | 1998-10-06 | — | — | US | disclosed |