Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410339 | 0.82 | PPARA (0.55) | KMT2AMEN1TP53NPC1RAB9A | |
| SCHEMBL6356958 | 0.79 | ALDH1A1 (0.44) | KMT2AMEN1NPC1RAB9APPARG | |
| SCHEMBL6353457 | 0.76 | ALDH1A1 (0.45) | KMT2AMEN1NPC1RAB9APPARG | |
| SCHEMBL29079329 | 0.74 | PPARA (0.56) | KMT2ARAB9APPARGPPARASMN1; SMN2 | |
| SCHEMBL6355161 | 0.74 | ALDH1A1 (0.46) | KMT2AMEN1RAB9ALMNAMAPT | |
| SCHEMBL8413216 | 0.72 | MAPK1 (0.51) | KMT2AMEN1TP53NPC1RAB9A | |
| SCHEMBL82055 | 0.72 | PPARG (0.53) | KMT2AMEN1PPARGPPARAMAPT | |
| SCHEMBL8935937 | 0.72 | PPARG (0.53) | KMT2AMEN1PPARGPPARAMAPT | |
| SCHEMBL9417313 | 0.72 | PPARA (0.53) | KMT2AMEN1PPARGPPARAMAPT | |
| SCHEMBL2701228 | 0.72 | MAPK1 (0.56) | KMT2AMEN1TP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872282-A | MAINTAIN OXYGEN AFFINITY IN BLOOD WHEN STORED | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1999-02-16 | — | — | US | disclosed |