Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413212 | 0.72 | KMT2A (0.46) | MAPK1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL5266201 | 0.72 | PPARA (0.48) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL17662382 | 0.72 | PPARA (0.46) | KMT2ANPC1RAB9AMEN1HPGD | |
| SCHEMBL2701228 | 0.72 | MAPK1 (0.56) | MAPK1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL27871203 | 0.68 | KMT2A (0.73) | KMT2ANPC1RAB9ATP53MEN1 | |
| SCHEMBL3984703 | 0.68 | ALDH1A1 (0.63) | MAPK1KMT2ARAB9ATP53MEN1 | |
| SCHEMBL5724626 | 0.66 | PPARA (0.58) | CYP2C9 | |
| SCHEMBL6650154 | 0.66 | KMT2A (0.68) | MAPK1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL8042023 | 0.66 | KMT2A (0.51) | MAPK1KMT2ANPC1RAB9ATP53 | |
| Efaproxiral SCHEMBL1649963 | 0.66 | PPARA (0.54) | KMT2ARAB9AMEN1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872282-A | MAINTAIN OXYGEN AFFINITY IN BLOOD WHEN STORED | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1999-02-16 | — | — | US | disclosed |