Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 3/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414335 | 0.86 | TAS1R3 (0.46) | RAD52AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8415046 | 0.85 | AOX1 (0.53) | RAD52AOX1UHRF1MEN1KMT2A | |
| SCHEMBL7569008 | 0.84 | TAS1R3 (0.44) | RAD52AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8414087 | 0.83 | AOX1 (0.46) | RAD52AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8411181 | 0.82 | RAD52 (0.47) | RAD52AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8415065 | 0.79 | AOX1 (0.47) | RAD52AOX1UHRF1MEN1KMT2A | |
| SCHEMBL8411691 | 0.79 | MAPT (0.52) | RAD52AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7567999 | 0.78 | AOX1 (0.47) | RAD52AOX1MEN1KMT2APDE3B | |
| SCHEMBL7569139 | 0.78 | AOX1 (0.45) | RAD52AOX1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8411863 | 0.78 | RAD52 (0.43) | RAD52AOX1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |