Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 4/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565793 | 0.88 | MAPT (0.40) | TAS1R3TAS1R1TP53RXFP1KMT2A | |
| SCHEMBL7571929 | 0.87 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL7566344 | 0.85 | HDAC1 (0.48) | TAS1R3TAS1R1TAS1R2RAD52KMT2A | |
| SCHEMBL7566996 | 0.85 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2RAD52TP53 | |
| SCHEMBL7564769 | 0.85 | RAD52 (0.59) | TAS1R3TAS1R1TAS1R2RAD52TP53 | |
| SCHEMBL8413337 | 0.84 | RAD52 (0.49) | TAS1R3TAS1R1TAS1R2RAD52TP53 | |
| SCHEMBL7568076 | 0.83 | AOX1 (0.45) | TAS1R3TAS1R1TAS1R2RAD52TP53 | |
| SCHEMBL7566165 | 0.83 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2RAD52TP53 | |
| SCHEMBL7567031 | 0.82 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2RAD52TP53 | |
| SCHEMBL7565766 | 0.80 | AOX1 (0.46) | TAS1R3TAS1R1TAS1R2RAD52TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |