Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CTH | P32929 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862320 | 1.00 | NR4A1 (0.47) | NR4A1MAOATOP2ACYP1A2CYP2C19 | |
| SCHEMBL215448 | 0.81 | NR4A1 (0.52) | NR4A1MAOATOP2ACYP1A2CYP2C19 | |
| SCHEMBL215449 | 0.81 | NR4A1 (0.52) | NR4A1MAOATOP2ACYP1A2CYP2C19 | |
| SCHEMBL214112 | 0.81 | G6PC1 (0.51) | NR4A1MAOATOP2ACYP1A2MEN1 | |
| SCHEMBL214111 | 0.81 | G6PC1 (0.51) | NR4A1MAOATOP2ACYP1A2MEN1 | |
| SCHEMBL840812 | 0.79 | NR4A1 (0.50) | NR4A1MAOATOP2ACYP1A2CYP2C19 | |
| SCHEMBL862025 | 0.79 | NR4A1 (0.50) | NR4A1MAOATOP2ACYP1A2CYP2C19 | |
| SCHEMBL213146 | 0.77 | NR4A1 (0.55) | NR4A1MAOATOP2ACYP1A2CYP2C19 | |
| SCHEMBL213145 | 0.77 | NR4A1 (0.55) | NR4A1MAOATOP2ACYP1A2CYP2C19 | |
| SCHEMBL862317 | 0.77 | NR4A1 (0.47) | NR4A1MAOATOP2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054387-B1 | PROCESS FOR THE MANUFACTURE OF HI-6 DIMETHANESULFONATE | PHOENIX CHEMICALS LTD (GB) | 2012-11-21 | — | — | EP | disclosed |
| US-8143406-B2 | Process for the manufacture of HI-6 dimethanesulfonate | PHOENIX CHEMICALS LIMITED (GB) | 2012-03-27 | — | — | US | disclosed |
| US-20100016604-A1 | PROCESS FOR THE MANUFACTURE OF HI-6 DIMETHANESULFONATE | PHOENIX CHEMICALS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| EP-2054387-A1 | PROCESS FOR THE MANUFACTURE OF HI-6 DIMETHANESULFONATE | Phoenix Chemicals Limited (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008023205-A1 | PROCESS FOR THE MANUFACTURE OF HI-6 DIMETHANESULFONATE | PHOENIX CHEMICALS LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016604-A1 | PROCESS FOR THE MANUFACTURE OF HI-6 DIMETHANESULFONATE | DHX36, HAAO, INTS6 | NR4A1 3416/4885MAOA 212/4885TOP2A 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.