Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTH | P32929 | 1/20 | 0.45 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213146 | 1.00 | NR4A1 (0.55) | NR4A1MAOAMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6166204 | 0.98 | NR4A1 (0.53) | NR4A1MAOAMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6166208 | 0.98 | NR4A1 (0.53) | NR4A1MAOAMEN1NPC1RAB9A | |
| SCHEMBL215448 | 0.81 | NR4A1 (0.52) | NR4A1MAOAMEN1NPC1RAB9A | |
| SCHEMBL215449 | 0.81 | NR4A1 (0.52) | NR4A1MAOAMEN1NPC1RAB9A | |
| SCHEMBL878896 | 0.80 | NR4A1 (0.55) | NR4A1MAOAMEN1NPC1RAB9A | |
| SCHEMBL840812 | 0.79 | NR4A1 (0.50) | NR4A1MAOAMEN1NPC1RAB9A | |
| SCHEMBL862025 | 0.79 | NR4A1 (0.50) | NR4A1MAOAMEN1NPC1RAB9A | |
| SCHEMBL215884 | 0.79 | NR4A1 (0.50) | NR4A1MAOAMEN1NPC1RAB9A | |
| SCHEMBL9085905 | 0.77 | MAOA (0.55) | NR4A1MAOAMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-8673932-B2 | Oxime substituted imidazo-containing compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-03-18 | — | — | US | disclosed |
| US-8673932-B2 | Oxime substituted imidazo-containing compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-03-18 | — | — | US | disclosed |
| US-8541509-B2 | Polymers functionalized with protected oxime compounds | BRIDGESTONE CORPORATION (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-1913036-B1 | AMINE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-8378102-B2 | Oxime and hydroxylamine substituted thiazolo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-19 | — | — | US | disclosed |
| US-8378102-B2 | Oxime and hydroxylamine substituted thiazolo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
| WO-2007120121-A2 | OXIME AND HYDROXYLAMINE SUBSTITUTED THIAZOLO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070066639-A1 | Oxime substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-03-22 | — | — | US | disclosed |
| US-20070066639-A1 | Oxime substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2007-03-22 | — | — | US | disclosed |
| WO-2007015872-A1 | AMINE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2007-02-08 | — | — | WO | disclosed |
| EP-1436282-B1 | SYNTHESIS OF 4-(PIPERIDYL) (2-PYRIDYL)METHANONE-(E)-O-METHYLOXIME AND ITS SALTS | SCHERING CORP (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1436282-A1 | SYNTHESIS OF 4-(PIPERIDYL) (2-PYRIDYL)METHANONE-(E)-O-METHYLOXIME AND ITS SALTS | SCHERING CORPORATION (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033488-A1 | SYNTHESIS OF 4-(PIPERIDYL) (2-PYRIDYL)METHANONE-(E)-O-METHYLOXIME AND ITS SALTS | SCHERING CORPORATION (US) | 2003-04-24 | — | — | WO | disclosed |
| US-4786648-A | ANALGESIC | WARNER-LAMBERT COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0271798-A2 | O-Substituted tetrahydropyridine oxime cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066639-A1 | Oxime substituted imidazoquinolines | IFNG, IRF3, IL2 | NR4A1 483/4885MAOA 1216/4885MEN1 4159/4885 |
| US-20160272742-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | FTH1, TFRC, FDPS | NR4A1 3251/4885MAOA 1692/4885MEN1 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.