Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410572 | 0.90 | KMT2A (0.42) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8413103 | 0.88 | L3MBTL1 (0.41) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL8411656 | 0.82 | L3MBTL1 (0.42) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL8409839 | 0.79 | KMT2A (0.41) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8412352 | 0.79 | CYP2D6 (0.47) | KMT2ACYP2C19DRD2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8413001 | 0.79 | L3MBTL1 (0.41) | MEN1KMT2ACYP1A2CYP2C19DRD2 | |
| SCHEMBL8413732 | 0.77 | MEN1 (0.39) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8412330 | 0.76 | TYR (0.41) | KMT2ANPSR1DRD2SMN1; SMN2MAPK1 | |
| SCHEMBL6997228 | 0.74 | HTR7 (0.49) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8413751 | 0.74 | HTR7 (0.46) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |