Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413103 | 0.94 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL8413573 | 0.89 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL8413001 | 0.82 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL8413640 | 0.82 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL8413423 | 0.81 | HTR7 (0.43) | L3MBTL1MEN1KMT2AATMKDM4E | |
| SCHEMBL8412352 | 0.79 | CYP2D6 (0.47) | KMT2AALDH1A1CYP2D6CYP2C19LMNA | |
| SCHEMBL8410173 | 0.77 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL8410491 | 0.76 | TP53 (0.40) | MAPTLMNASMN1; SMN2HTR1AADRA2A | |
| SCHEMBL8412349 | 0.76 | L3MBTL1 (0.42) | L3MBTL1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL8412330 | 0.76 | TYR (0.41) | L3MBTL1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |