Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413913 | 0.93 | GRIA2 (0.51) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8414119 | 0.83 | GRIA2 (0.54) | VCAM1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8415885 | 0.76 | GRIA2 (0.59) | VCAM1POLBGRIA1GRIA2GRIA3 | |
| SCHEMBL8415935 | 0.75 | GRIA2 (0.50) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8414072 | 0.72 | MAPT (0.47) | SMN1; SMN2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8413952 | 0.72 | GRIA2 (0.53) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8415292 | 0.69 | GRIA2 (0.65) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL31236083 | 0.69 | GRIA2 (0.65) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8414052 | 0.69 | GRIA2 (0.65) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL8415895 | 0.68 | SMN1; SMN2 (0.62) | VCAM1POLBSMN1; SMN2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912245-A | AMPA AND KAINATE ANTAGONISTS. | EGIS GYOGYSZERGYAR RT. (HU) | 1999-06-15 | — | — | US | disclosed |