Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413952 | 0.84 | GRIA2 (0.53) | MAPTLMNAGRIA1GRIA2GRIA3 | |
| SCHEMBL8413733 | 0.81 | LMNA (0.49) | MAPTLMNAGRIA1GRIA2GRIA3 | |
| SCHEMBL8415259 | 0.78 | GRIA2 (0.51) | MAPTLMNAGRIA1GRIA2GRIA3 | |
| SCHEMBL4163164 | 0.76 | KMT2A (0.57) | LMNACA12CA2CA9ALDH1A1 | |
| SCHEMBL8520382 | 0.76 | KDM4E (0.58) | MAPTCYP3A4ALDH1A1KMT2A | |
| SCHEMBL8415885 | 0.75 | GRIA2 (0.59) | MAPTLMNAGRIA1GRIA2GRIA3 | |
| SCHEMBL8414084 | 0.74 | PARP1 (0.53) | MAPTLMNAGRIA1GRIA2GRIA3 | |
| SCHEMBL8415265 | 0.73 | PKM (0.56) | HPGDTSHRSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8413913 | 0.73 | GRIA2 (0.51) | MAPTLMNAGRIA1GRIA2GRIA3 | |
| SCHEMBL8413837 | 0.72 | VCAM1 (0.47) | MAPTLMNAGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912245-A | AMPA AND KAINATE ANTAGONISTS. | EGIS GYOGYSZERGYAR RT. (HU) | 1999-06-15 | — | — | US | disclosed |