Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415905 | 0.87 | TYR (0.40) | TYRESR1ESR2APPMEN1 | |
| SCHEMBL8144830 | 0.75 | PTGS1 (0.36) | ESR1ESR2CYP3A4ALOX5PTGS1 | |
| SCHEMBL8141137 | 0.74 | TDP1 (0.46) | KMT2ATDP1GAAL3MBTL1 | |
| SCHEMBL2160179 | 0.74 | SMN1; SMN2 (0.40) | TYRMEN1TP53CYP3A4MAPT | |
| SCHEMBL1823336 | 0.72 | TYR (0.50) | TYRAPPMEN1TP53CYP3A4 | |
| SCHEMBL1823337 | 0.72 | TYR (0.50) | TYRAPPMEN1TP53CYP3A4 | |
| SCHEMBL6154475 | 0.71 | PTGS2 (0.43) | ESR1MEN1TP53MAPTHTT | |
| SCHEMBL1823738 | 0.70 | TYR (0.53) | TYRAPPMEN1TP53CYP3A4 | |
| SCHEMBL3430982 | 0.70 | ALDH1A1 (0.50) | TYRESR1ESR2APPMEN1 | |
| SCHEMBL1823735 | 0.70 | TYR (0.53) | TYRAPPMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724565-B1 | NOVEL SPIN TRAP NITRONYL HINDERED PHENOLS | OKLAHOMA MED RES FOUND (US) | 1999-08-18 | — | — | EP | claimed |