Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652524 | 0.90 | EGFR (0.46) | EGFRMAPK1ALDH1A1 | |
| SCHEMBL2958752 | 0.88 | CA12 (0.48) | PPARDEGFRMAPK1MAOBCA12 | |
| SCHEMBL3297236 | 0.84 | PPARD (0.43) | PPARDMAPK1MAOBPLA2G4ACA12 | |
| SCHEMBL5840947 | 0.81 | TSHR (0.40) | EGFRMAPK1ALDH1A1TSHR | |
| SCHEMBL6363526 | 0.80 | ADRB2 (0.40) | PPARDEGFRMAPK1MAOB | |
| SCHEMBL4805729 | 0.80 | EGFR (0.52) | EGFRCA12CA1CA2TSHR | |
| SCHEMBL9058674 | 0.80 | MAPK1 (0.68) | MAPK1ALDH1A1TSHR | |
| SCHEMBL4653417 | 0.80 | MAOB (0.42) | PPARDMAOBCA12ALDH1A1CA1 | |
| SCHEMBL4654683 | 0.79 | ALOX15 (0.48) | PPARDMAOB | |
| SCHEMBL7785544 | 0.79 | LTA4H (0.46) | EGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | claimed |
| EP-0643035-B1 | DERMATOLOGIC PREPARATION AND NOVEL BENZOIC ACID DERIVATIVE | KAO CORP (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | disclosed |
| WO-1996017589-A1 | METHOD OF SMOOTHING OR REMOVING WRINKLES AND METHOD OF STIMULATING COLLAGEN SYNTHESIS | KAO CORPORATION (JP) | 1996-06-13 | — | — | WO | disclosed |
| EP-0643035-A1 | DERMATOLOGIC PREPARATION AND NOVEL BENZOIC ACID DERIVATIVE | Kao Corporation (JP) | 1995-03-15 | — | — | EP | disclosed |