Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296702 | 0.90 | TSHR (0.52) | LMNAMAPTGAACCR5POLB | |
| SCHEMBL8293088 | 0.88 | NPC1 (0.46) | LMNADRD2DRD4DRD3PDE5A | |
| SCHEMBL8293091 | 0.88 | NPC1 (0.46) | LMNADRD2DRD4DRD3PDE5A | |
| SCHEMBL8293460 | 0.83 | MAPT (0.52) | LMNAPDE5AMAPTGAAPOLB | |
| SCHEMBL8436830 | 0.80 | GAA (0.54) | LMNAGAAPOLB | |
| SCHEMBL8292542 | 0.79 | PDE5A (0.53) | LMNAPDE5AGAA | |
| SCHEMBL8292075 | 0.79 | NPC1 (0.47) | LMNAPDE5AMAPTGAAHPGD | |
| SCHEMBL8292073 | 0.79 | NPC1 (0.47) | LMNAPDE5AMAPTGAAHPGD | |
| SCHEMBL6939363 | 0.79 | GAA (0.48) | LMNADRD2DRD4DRD3PDE5A | |
| SCHEMBL8572500 | 0.78 | DRD2 (0.44) | LMNADRD2DRD4DRD3PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |