Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300888 | 0.90 | POLB (0.64) | GAAPOLBLMNAL3MBTL1KMT2A | |
| SCHEMBL8301263 | 0.88 | POLB (0.50) | GAAPOLBHSP90AA1LMNAL3MBTL1 | |
| SCHEMBL8292747 | 0.87 | HSP90AA1 (0.55) | HSP90AA1LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL8299249 | 0.80 | POLB (0.61) | GAAPOLBLMNAL3MBTL1KMT2A | |
| SCHEMBL8414604 | 0.80 | LMNA (0.46) | GAAPOLBLMNA | |
| SCHEMBL8297193 | 0.78 | POLB (0.58) | GAAPOLBKMT2AALDH1A1KDM4E | |
| SCHEMBL8292069 | 0.77 | HSP90AA1 (0.52) | GAAHSP90AA1LMNAL3MBTL1KMT2A | |
| SCHEMBL8301388 | 0.77 | POLB (0.48) | GAAPOLBLMNAALDH1A1KDM4E | |
| SCHEMBL8297238 | 0.76 | POLB (0.53) | GAAPOLBLMNAL3MBTL1KMT2A | |
| SCHEMBL8301379 | 0.76 | HSD17B10 (0.69) | POLBHSP90AA1LMNANAMPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |