Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414604 | 0.90 | LMNA (0.46) | GAALMNAPOLBCCR5MAPT | |
| SCHEMBL8301263 | 0.83 | POLB (0.50) | TSHRGAAL3MBTL1LMNAKDM4E | |
| SCHEMBL8293460 | 0.80 | MAPT (0.52) | GAALMNAPOLBMAPK1MAPT | |
| SCHEMBL8293088 | 0.79 | NPC1 (0.46) | TSHRGAALMNAKDM4EMEN1 | |
| SCHEMBL8293091 | 0.79 | NPC1 (0.46) | TSHRGAALMNAKDM4EMEN1 | |
| SCHEMBL8300681 | 0.78 | GAA (0.60) | TSHRGAAL3MBTL1LMNAKDM4E | |
| SCHEMBL8294814 | 0.78 | MAPT (0.52) | TSHRGAAL3MBTL1LMNAKDM4E | |
| SCHEMBL8299688 | 0.77 | LMNA (0.44) | TSHRGAALMNAKDM4EPOLB | |
| SCHEMBL8297193 | 0.77 | POLB (0.58) | TSHRGAAKDM4EPOLBKMT2A | |
| SCHEMBL8299687 | 0.77 | LMNA (0.44) | TSHRGAALMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |