Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411223 | 1.00 | FUCA1 (0.41) | FUCA1LMNAGAATACR3ALDH1A1 | |
| SCHEMBL8411390 | 0.90 | HSD11B1 (0.43) | FUCA1LMNAGAATACR3ALDH1A1 | |
| SCHEMBL27463118 | 0.81 | LMNA (0.48) | LMNAGAATACR3ALDH1A1POLB | |
| SCHEMBL4422938 | 0.79 | NPC1 (0.53) | LMNAGAAALDH1A1NPC1RAB9A | |
| SCHEMBL3094922 | 0.76 | TACR1 (0.38) | FUCA1GAAMAPTNPC1RAB9A | |
| SCHEMBL6704820 | 0.76 | TACR1 (0.38) | FUCA1GAAMAPTNPC1RAB9A | |
| SCHEMBL4052147 | 0.75 | RAB9A (0.56) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8413126 | 0.75 | FUCA1 (0.37) | FUCA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8411492 | 0.75 | FUCA1 (0.37) | FUCA1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6705224 | 0.75 | TEAD1 (0.43) | LMNAGAATACR3ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952322-A | AMIDE-SUBSTITUTED BENZIMIDAZOLE, INDOLE DERIVATIVES | PFIZER INC. (US) | 1999-09-14 | — | — | US | claimed |
| US-5952322-A | AMIDE-SUBSTITUTED BENZIMIDAZOLE, INDOLE DERIVATIVES | PFIZER INC. (US) | 1999-09-14 | — | — | US | disclosed |