SCHEMBL8415134

SCHEMBL8415134

CO[Si](C)(c1ccccc1)[Si](OC)(OC)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CA4 P22748 1/20 0.33
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9466367 0.85 ESR1 (0.41) ESR1ESR2CA4POLB
SCHEMBL648335 0.83 CA4 (0.41) ESR1ESR2CA4POLB
SCHEMBL8414146 0.81 ESR1 (0.38) ESR1ESR2CA4POLB
SCHEMBL8639620 0.81 ESR1 (0.38) ESR1ESR2CA4POLB
SCHEMBL8638732 0.79 ESR1 (0.37) ESR1ESR2CA4POLB
SCHEMBL8412770 0.79 ESR1 (0.37) ESR1ESR2CA4POLB
SCHEMBL8642194 0.79 ESR1 (0.37) ESR1ESR2CA4POLB
SCHEMBL8414396 0.79 CA4 (0.40) ESR1ESR2CA4POLB
SCHEMBL8415126 0.79 CA4 (0.40) ESR1ESR2CA4POLB
SCHEMBL9684356 0.79 ESR1 (0.37) ESR1ESR2CA4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669363-B1 Process for preparing polyorganosilane TOSHIBA SILICONE (JP) 1999-08-18 EP disclosed
EP-0641820-B1 Organosilicon polymer and process for the preparation thereof TOSHIBA SILICONE (JP) 1998-08-12 EP disclosed
US-5633312-A Process for preparing polyorganosilane TOSHIBA SILICONE CO., LTD. (JP) 1997-05-27 US disclosed
US-5489662-A Process for the preparation of organosilicon polymer TOSHIBA SILICONE CO., LTD. (JP) 1996-02-06 US disclosed
EP-0669363-A2 Process for preparing polyorganosilane TOSHIBA SILICONE CO., LTD. (JP) 1995-08-30 EP disclosed
EP-0641820-A1 Process for the preparation of organosilicon polymer TOSHIBA SILICONE CO., LTD. (JP) 1995-03-08 EP disclosed