Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639620 | 0.90 | ESR1 (0.38) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL8416106 | 0.87 | ESR1 (0.37) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL9684356 | 0.87 | ESR1 (0.37) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL8642194 | 0.87 | ESR1 (0.37) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL8415126 | 0.87 | CA4 (0.40) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL8638732 | 0.87 | ESR1 (0.37) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL8415134 | 0.85 | ESR1 (0.35) | ESR1ESR2CA4POLB | |
| SCHEMBL10359999 | 0.80 | CA4 (0.34) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL704149 | 0.78 | CA1 (0.41) | ESR1ESR2CA4CA12CA1 | |
| SCHEMBL48955 | 0.78 | ESR1 (0.41) | ESR1ESR2CA4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250646-A | Reacting disilane with organometallic compound | WACKER-CHEMIE GMBH (DE) | 1993-10-05 | — | — | US | disclosed |
| US-5166287-A | Reaction of a disilane to form polysiloxanes | WACKER-CHEMIE GMBH (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0486946-A2 | Process for the production of metallopolysilanes and their use | Wacker-Chemie GmbH (DE) | 1992-05-27 | — | — | EP | disclosed |
| EP-0463624-A2 | Process for preparing organopolysilanes | WACKER-CHEMIE GMBH (DE) | 1992-01-02 | — | — | EP | disclosed |