SCHEMBL8415296

SCHEMBL8415296

O=C(c1ccccc1)c1ccc(C2=CC=CCC2=S)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 5/20 0.42
SRD5A2 P31213 1/20 0.42
HPGD P15428 4/20 0.41
NPC1 O15118 3/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
ELANE P08246 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPK13 O15264 1/20 0.38
MAPK12 P53778 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446539 0.82 ALDH1A1 (0.32) ALDH1A1MAPK1
SCHEMBL7478487 0.78 ALDH1A1 (0.43) RAB9AMAPTMEN1KMT2AALDH1A1
SCHEMBL1370686 0.72 CYP3A4 (0.37) MAPTMEN1KMT2AALDH1A1TDP1
Benzophenone SCHEMBL9310484 0.70 ALDH1A1 (0.52) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL197633 0.70 RAB9A (0.82) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL13019488 0.70 RAB9A (0.82) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL6903428 0.70 ALDH1A1 (0.50) RAB9AMAPTMEN1KMT2AALDH1A1
SCHEMBL10338604 0.69 ACE2 (0.39) LMNAKMT2AALDH1A1HPGDTDP1
SCHEMBL5898964 0.68
SCHEMBL41657 0.68 RAB9A (0.78) RAB9ALMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934247-A1 PHOTOINITIATORS Lambson Fine Chemicals Limited (GB) 1999-08-11 EP claimed
WO-1997049664-A1 PHOTOINITIATORS LAMBSON FINE CHEMICALS LIMITED (GB) 1997-12-31 WO claimed
CN-108884110-A Sulfonium salt, photoacid generator, Photocurable composition and its solidified body 三亚普罗股份有限公司 2018-11-23 CN disclosed
EP-0934247-A1 PHOTOINITIATORS Lambson Fine Chemicals Limited (GB) 1999-08-11 EP disclosed
WO-1997049664-A1 PHOTOINITIATORS LAMBSON FINE CHEMICALS LIMITED (GB) 1997-12-31 WO disclosed