Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 11/20 | 0.42 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.42 |
| ▸ | INPP5B | P32019 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959555 | 0.76 | POLB (0.50) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL19506399 | 0.76 | TYR (0.46) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL9736712 | 0.75 | CYP2A6 (0.42) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL16486728 | 0.75 | INPPL1 (0.50) | INPPL1INPP5AUSP2GAAALOX15 | |
| SCHEMBL30630348 | 0.75 | MEN1 (0.58) | INPPL1INPP5ATYRKDM4EALDH1A1 | |
| SCHEMBL9442085 | 0.74 | BACE1 (0.42) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL8389196 | 0.74 | INPPL1 (0.67) | INPPL1INPP5AINPP5BUSP2AKT1 | |
| SCHEMBL8770822 | 0.74 | INPPL1 (0.50) | INPPL1INPP5AINPP5BUSP2GAA | |
| SCHEMBL30833152 | 0.73 | BACE1 (0.41) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL15952462 | 0.73 | BACE1 (0.41) | TYRUSP2GAAALOX15RAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597022-B2 | PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES | OREAL (FR) | 1999-11-17 | — | — | EP | claimed |
| US-5874091-A | PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. | L'OREAL (FR) | 1999-02-23 | — | — | US | claimed |
| US-5645609-A | Compositions which contain and processes which use an insoluble pigment obtained by the oxidative polymerization of indole derivatives for the temporary dyeing of keratinous fibers | L'OREAL (FR) | 1997-07-08 | — | — | US | claimed |
| US-5874091-A | PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. | L'OREAL (FR) | 1999-02-23 | — | — | US | disclosed |
| US-5645609-A | Compositions which contain and processes which use an insoluble pigment obtained by the oxidative polymerization of indole derivatives for the temporary dyeing of keratinous fibers | L'OREAL (FR) | 1997-07-08 | — | — | US | disclosed |