SCHEMBL8415463

SCHEMBL8415463

C=C(C)C(=O)Oc1c(C)cccc1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.71
HSD17B10 Q99714 4/20 0.71
ALDH1A1 P00352 3/20 0.71
HPGD P15428 3/20 0.71
MAPK1 P28482 1/20 0.49
MYC P01106 2/20 0.44
ELANE P08246 1/20 0.43
CYP2C9 P11712 3/20 0.41
KMT2A Q03164 3/20 0.41
CYP3A4 P08684 2/20 0.41
PTGS1 P23219 2/20 0.41
PTGS2 P35354 2/20 0.41
NAPRT Q6XQN6 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
TSHR P16473 1/20 0.41
GGT1 P19440 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL447625 0.86 ALDH1A1 (0.49) KDM4EHSD17B10ALDH1A1HPGDELANE
SCHEMBL28210923 0.85 MAPK1 (0.68) KDM4EHSD17B10ALDH1A1HPGDMAPK1
SCHEMBL1623883 0.84 KDM4E (0.50) KDM4EHSD17B10ALDH1A1HPGDMAPK1
Zinc Ion SCHEMBL1623671 0.84 KDM4E (0.50) KDM4EHSD17B10ALDH1A1HPGDMAPK1
SCHEMBL1623445 0.84 KDM4E (0.50) KDM4EHSD17B10ALDH1A1HPGDMAPK1
SCHEMBL1315833 0.83 KDM4E (1.00) KDM4EHSD17B10ALDH1A1HPGDMAPK1
SCHEMBL29760302 0.83 KDM4E (1.00) KDM4EHSD17B10ALDH1A1HPGDMAPK1
SCHEMBL4397553 0.80 KDM4E (0.75) KDM4EHSD17B10ALDH1A1HPGDMAPK1
SCHEMBL15496003 0.80 KDM4E (0.44) KDM4EHSD17B10ALDH1A1HPGDELANE
SCHEMBL8528074 0.79 KDM4E (0.42) KDM4EHSD17B10ALDH1A1HPGDELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833870-B1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN AS (NO) 1999-09-08 EP claimed
US-20070287097-A1 Aluminum support containing multilayer alkali-soluble resin and a light to heat conversion material; sensitivity, chemical resistance KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-13 US disclosed
US-20070287097-A1 Aluminum support containing multilayer alkali-soluble resin and a light to heat conversion material; sensitivity, chemical resistance KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-13 US disclosed
EP-1347014-B1 Infrared-photosensitive composition FUJIFILM CORP (JP) 2007-07-11 EP disclosed
US-7217498-B2 Multilayer; support with image forming layer containing water insoluble polymer and soluble in alkaline aqueous solutions FUJIFILM CORPORATION (JP) 2007-05-15 US disclosed
US-7217498-B2 Multilayer; support with image forming layer containing water insoluble polymer and soluble in alkaline aqueous solutions FUJIFILM CORPORATION (JP) 2007-05-15 US disclosed
US-7217501-B2 Infrared-sensitive lithographic printing plate FUJIFILM CORPORATION (JP) 2007-05-15 US disclosed
US-7217501-B2 Infrared-sensitive lithographic printing plate FUJIFILM CORPORATION (JP) 2007-05-15 US disclosed