Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7716226 | 0.82 | PNMT (0.35) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2806871 | 0.81 | PNMT (0.33) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2801807 | 0.81 | NPC1 (0.37) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6904823 | 0.81 | PNMT (0.33) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL812556 | 0.78 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2805378 | 0.77 | PNMT (0.32) | PNMT | |
| SCHEMBL5823610 | 0.70 | PNMT (0.41) | PNMTNPC1RAB9A | |
| SCHEMBL8416820 | 0.69 | PNMT (0.34) | PNMTNPC1RAB9A | |
| SCHEMBL7602502 | 0.68 | PNMT (0.35) | PNMTNPC1RAB9A | |
| SCHEMBL7602996 | 0.68 | PNMT (0.35) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880302-A | Organometallic compound | TARGOR GMBH (DE) | 1999-03-09 | — | — | US | claimed |
| US-5880302-A | Organometallic compound | TARGOR GMBH (DE) | 1999-03-09 | — | — | US | disclosed |