Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.49 |
| ▸ | HPD | P32754 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341109 | 0.87 | SGMS2 (0.62) | KMT2AALDH1A1PARP1SGMS2PTGER1 | |
| SCHEMBL14609985 | 0.86 | KMT2A (0.63) | KMT2AALDH1A1PARP1KDM4ESGMS2 | |
| SCHEMBL5839101 | 0.86 | ALDH1A1 (0.59) | KMT2AALDH1A1SMN1; SMN2PARP1RXRA | |
| SCHEMBL21443892 | 0.85 | ABCB1 (0.52) | ALDH1A1SMN1; SMN2PARP1RXRAKDM4E | |
| SCHEMBL29254214 | 0.84 | PARP1 (0.54) | KMT2ASMN1; SMN2PARP1SGMS2RAB9A | |
| SCHEMBL8415759 | 0.83 | HTT (0.59) | KMT2AALDH1A1SMN1; SMN2PARP1RXRA | |
| SCHEMBL21327456 | 0.82 | LRRK2 (0.57) | ALDH1A1SMN1; SMN2KDM4ESGMS2PTGER1 | |
| SCHEMBL13819477 | 0.82 | MCL1 (0.54) | SMN1; SMN2PTGER1MAPTL3MBTL1 | |
| SCHEMBL2331143 | 0.80 | MAPT (0.65) | KMT2ASMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL990 | 0.76 | HCRTR1 (0.62) | KMT2AALDH1A1KDM4ERAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |