Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415821 | 0.92 | KDM4E (0.53) | CHEK1PIM1MAPK8CLK4CYP1A2 | |
| SCHEMBL7410354 | 0.88 | KMT2A (0.55) | KMT2AMEN1F10KDM4EMAPT | |
| SCHEMBL7413404 | 0.83 | KMT2A (0.64) | CHEK1PIM1MAPK8CLK4CYP1A2 | |
| SCHEMBL8417461 | 0.83 | KMT2A (0.64) | CHEK1PIM1MAPK8CLK4CYP1A2 | |
| SCHEMBL7409765 | 0.83 | NPC1 (0.46) | KDM4ETDP1RAB9ANPC1 | |
| SCHEMBL8414166 | 0.81 | CHEK1 (0.51) | CHEK1PIM1MAPK8CLK4CYP1A2 | |
| SCHEMBL7411534 | 0.81 | POLB (0.65) | CHEK1PIM1MAPK8CLK4KMT2A | |
| SCHEMBL7408481 | 0.81 | POLB (0.65) | CHEK1PIM1MAPK8CLK4KMT2A | |
| SCHEMBL7408194 | 0.79 | F10 (0.52) | KMT2APOLBMEN1F10KDM4E | |
| SCHEMBL8414778 | 0.79 | PDE4D (0.67) | CHEK1PIM1MAPK8CLK4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |