Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | TPMT | P51580 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413404 | 1.00 | KMT2A (0.64) | KMT2AMEN1CHEK1PIM1MAPK8 | |
| SCHEMBL8414778 | 0.88 | PDE4D (0.67) | KMT2AMEN1CHEK1PIM1MAPK8 | |
| SCHEMBL7409183 | 0.87 | MEN1 (0.84) | KMT2AMEN1NPC1F10CYP1A2 | |
| SCHEMBL7410644 | 0.87 | MEN1 (0.84) | KMT2AMEN1NPC1F10CYP1A2 | |
| SCHEMBL8414166 | 0.85 | CHEK1 (0.51) | KMT2AMEN1CHEK1PIM1MAPK8 | |
| SCHEMBL8415835 | 0.83 | CHEK1 (0.51) | KMT2AMEN1CHEK1PIM1MAPK8 | |
| SCHEMBL8414780 | 0.82 | ALDH1A1 (0.58) | KMT2AMEN1CHEK1PIM1MAPK8 | |
| SCHEMBL7411821 | 0.82 | ALDH1A1 (0.58) | KMT2AMEN1CHEK1PIM1MAPK8 | |
| SCHEMBL2979309 | 0.82 | CA12 (0.64) | KMT2AMEN1CHEK1PIM1MAPK8 | |
| SCHEMBL27837488 | 0.81 | CYP1A2 (0.66) | KMT2AMEN1CHEK1PIM1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |