Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411534 | 1.00 | POLB (0.65) | POLBLMNAMAPTPDE4DCHEK1 | |
| SCHEMBL7410267 | 0.87 | F10 (0.57) | POLBLMNAMAPTALDH1A1TDP1 | |
| SCHEMBL7411059 | 0.87 | F10 (0.57) | POLBLMNAMAPTALDH1A1TDP1 | |
| SCHEMBL8415828 | 0.87 | RAB9A (0.51) | MAPTTDP1MEN1KMT2ATP53 | |
| SCHEMBL8414778 | 0.86 | PDE4D (0.67) | POLBLMNAMAPTPDE4DCHEK1 | |
| SCHEMBL8417467 | 0.83 | KMT2A (0.53) | POLBLMNAMAPTPDE4DCHEK1 | |
| SCHEMBL8414166 | 0.83 | CHEK1 (0.51) | POLBLMNAMAPTPDE4DCHEK1 | |
| SCHEMBL8415821 | 0.81 | KDM4E (0.53) | POLBLMNAMAPTPDE4DCHEK1 | |
| SCHEMBL8415835 | 0.81 | CHEK1 (0.51) | POLBLMNAMAPTPDE4DCHEK1 | |
| SCHEMBL7411821 | 0.80 | ALDH1A1 (0.58) | POLBLMNAMAPTPDE4DCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | claimed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |