Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29810510 | 0.85 | ALDH1A1 (0.49) | PARP10ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL12656352 | 0.83 | CA1 (0.48) | PARP10ALDH1A1MAPTPRSS1PRSS2 | |
| SCHEMBL28689791 | 0.82 | ALDH1A1 (0.50) | PARP10ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL8006543 | 0.79 | PARP10 (0.58) | PARP10ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL9846597 | 0.77 | PARP10 (0.59) | PARP10ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL4378408 | 0.75 | SMN1; SMN2 (0.43) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10548607 | 0.75 | PARP10 (0.56) | PARP10ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL1532229 | 0.74 | RXFP1 (0.48) | ALDH1A1KDM4ESMN1; SMN2TSHRNPC1 | |
| SCHEMBL6377733 | 0.74 | PARP10 (0.66) | PARP10ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL3832407 | 0.74 | ALDH1A1 (0.77) | PARP10ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714885-B1 | Preparation process of aminoacetamide derivative | EISAI CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0714885-A2 | Preparation process of aminoacetamide derivative | EISAI CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |