SCHEMBL841604

SCHEMBL841604

Cc1cccc2c(Cl)nc3ccccc3c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP1A2 P05177 1/20 0.44
GPR3 P46089 1/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP2A6 P11509 1/20 0.42
BACE1 P56817 1/20 0.42
ACHE P22303 1/20 0.41
MAPT P10636 2/20 0.41
TP53 P04637 1/20 0.41
KDM4E B2RXH2 3/20 0.40
ADORA2A P29274 1/20 0.40
GLA P06280 1/20 0.40
KMT2A Q03164 1/20 0.40
PKM P14618 1/20 0.40
METAP1 P53582 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24164244 0.81 GPR3 (0.61) POLBCYP1A2GPR3ALDH1A1CYP2A6
SCHEMBL12733667 0.78 SMN1; SMN2 (0.50) POLBMAOATDP1CYP1A2ALDH1A1
SCHEMBL28824684 0.78 CYP1A2 (0.44) POLBCYP1A2GPR3ALDH1A1CYP2A6
SCHEMBL856788 0.74 TDP1 (0.54) POLBMAOAMAOBTDP1CYP1A2
SCHEMBL29461212 0.74 TDP1 (0.54) POLBMAOAMAOBTDP1CYP1A2
SCHEMBL516091 0.73 TDP1 (0.59) POLBMAOAMAOBTDP1GPR3
SCHEMBL30666608 0.73 PDE3B (0.46) MAOAMAOBTDP1CYP1A2ALDH1A1
SCHEMBL9268529 0.73 TDP1 (0.48) POLBTDP1CYP1A2ALDH1A1CYP2A6
SCHEMBL23197724 0.73 POLB (0.63) POLBMAOAMAOBTDP1GPR3
SCHEMBL2879866 0.72 POLB (0.68) POLBMAOAMAOBTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP disclosed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US disclosed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP disclosed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US disclosed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP disclosed
EP-1981898-B2 Metal complexes of imidazo[1,2-f]phenanthridine ligands for use in OLED devices UNIVERSAL DISPLAY CORP (US) 2019-04-10 EP disclosed
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-21 US disclosed
CN-101415718-B Metal complexes of cyclometallated imidazo [1,2-f ] phenanthridine and diimidazo [1,2-a:1',2' -c ] quinazoline ligands and their isoelectronic and benzocyclo-analogs UNIVERSAL DISPLAY CORP 2013-05-29 CN disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
EP-2399922-A1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof Universal Display Corporation (US) 2011-12-28 EP disclosed
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF KNOWLES DAVID B 2011-03-31 US disclosed
US-7915415-B2 Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION (US) 2011-03-29 US disclosed
EP-2243785-A1 Phosphorescent condensed ring carbene metal complexes for use in organic light emitting devices Universal Display Corporation (US) 2010-10-27 EP disclosed
CN-101415718-A Cyclometallated imidazo [1 ] s UNIVERSAL DISPLAY CORP (US) 2009-04-22 CN disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF NDUFC1, CD274, CRY1 POLB 1522/4885MAOA 192/4885MAOB 985/4885
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 POLB 1435/4885MAOA 800/4885MAOB 1947/4885
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 POLB 1435/4885MAOA 800/4885MAOB 1947/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 POLB 2736/4885MAOA 4074/4885MAOB 3829/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C POLB 2770/4885MAOA 1681/4885MAOB 3257/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 POLB 1435/4885MAOA 800/4885MAOB 1947/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 POLB 1435/4885MAOA 800/4885MAOB 1947/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 POLB 2736/4885MAOA 4074/4885MAOB 3829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.