Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415390 | 0.94 | GAA (0.37) | GAAALDH1A1L3MBTL1LMNATSHR | |
| SCHEMBL8573582 | 0.90 | SMN1; SMN2 (0.38) | GAAALDH1A1L3MBTL1LMNATSHR | |
| SCHEMBL8413743 | 0.89 | PTGER3 (0.38) | — | |
| SCHEMBL8416979 | 0.85 | PTGER3 (0.35) | ALDH1A1KDM4EMAPT | |
| SCHEMBL8415964 | 0.83 | GAA (0.35) | GAAALDH1A1L3MBTL1TSHR | |
| SCHEMBL8572803 | 0.78 | CHRM3 (0.48) | — | |
| SCHEMBL8573046 | 0.75 | HTT (0.52) | ALDH1A1L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL8415966 | 0.74 | F2 (0.37) | ALDH1A1KDM4EMAPT | |
| SCHEMBL8575669 | 0.72 | CTSG (0.39) | GAAALDH1A1L3MBTL1LMNATSHR | |
| SCHEMBL7274642 | 0.69 | S1PR1 (0.41) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |