Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 7/20 | 0.33 |
| ▸ | F2 | P00734 | 7/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.33 |
| ▸ | HPN | P05981 | 4/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.33 |
| ▸ | HGFAC | Q04756 | 3/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413743 | 0.93 | PTGER3 (0.38) | PTGER3PTGER2F10F2PRSS1 | |
| SCHEMBL8415390 | 0.89 | GAA (0.37) | F2ALDH1A1 | |
| SCHEMBL8415966 | 0.88 | F2 (0.37) | PTGER3PTGER2F10F2PRSS1 | |
| SCHEMBL8416045 | 0.85 | GAA (0.39) | KDM4EALDH1A1MAPT | |
| SCHEMBL8415964 | 0.78 | GAA (0.35) | F10F2PRSS1HPNPRSS2 | |
| SCHEMBL8573582 | 0.74 | SMN1; SMN2 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL8572803 | 0.72 | CHRM3 (0.48) | F10F2PRSS1HPNPRSS2 | |
| SCHEMBL8575501 | 0.71 | PTGER3 (0.35) | PTGER3PTGER2 | |
| SCHEMBL11021780 | 0.70 | PTGER2 (0.62) | PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL8416012 | 0.70 | PTGER3 (0.35) | PTGER3PTGER2F10FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |