Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 3/20 | 0.39 |
| ▸ | CMA1 | P23946 | 3/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573438 | 0.94 | CTSG (0.40) | CTSGCMA1GRM2ELANEGAA | |
| Hydrochloric Acid SCHEMBL8571485 | 0.93 | CTSG (0.39) | CTSGCMA1GRM2ELANEGAA | |
| SCHEMBL8573886 | 0.84 | HDAC1 (0.40) | CTSGCMA1CHRM4CYP11B1CYP11B2 | |
| SCHEMBL8570127 | 0.82 | HTT (0.40) | CTSGCMA1ELANENR3C2PPARG | |
| SCHEMBL8575660 | 0.81 | GRM5 (0.43) | CHRM4CHRM2 | |
| SCHEMBL8571333 | 0.81 | PKM (0.38) | GRM2ALDH1A1LMNACYP11B1CYP11B2 | |
| SCHEMBL8571508 | 0.81 | HTR7 (0.37) | CTSGCMA1GRM2ELANETSHR | |
| SCHEMBL8572736 | 0.80 | OPRM1 (0.43) | ELANEALDH1A1MAPT | |
| SCHEMBL8417227 | 0.80 | CTSG (0.42) | CTSGCMA1GRM2GAAL3MBTL1 | |
| SCHEMBL8571584 | 0.79 | CTSG (0.39) | CTSGCMA1GAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |