SCHEMBL8416138

SCHEMBL8416138

c1ccc2c(c1)-c1ccccc1C2C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.52
ACHE P22303 1/20 0.52
IDO1 P14902 1/20 0.47
TDO2 P48775 1/20 0.47
PRCP P42785 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
PARP1 P09874 1/20 0.38
HTR2A P28223 2/20 0.38
HTR2C P28335 2/20 0.38
HTR2B P41595 2/20 0.38
HRH3 Q9Y5N1 2/20 0.38
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23704622 1.00 BCHE (0.52) BCHEACHEIDO1TDO2PRCP
SCHEMBL28225513 0.98 BCHE (0.48) BCHEACHEIDO1TDO2PRCP
SCHEMBL28142477 0.93 BCHE (0.44) BCHEACHEIDO1TDO2PRCP
SCHEMBL28946001 0.86 SLC18A3 (0.44) BCHEACHEIDO1TDO2CYP1A2
SCHEMBL29988938 0.84 ALDH1A1 (0.41) BCHEACHEIDO1TDO2PRCP
SCHEMBL8413706 0.80 BCHE (0.40) BCHEACHEIDO1TDO2PRCP
SCHEMBL8416176 0.80 IDO1 (0.38) BCHEACHEIDO1TDO2PRCP
SCHEMBL27746260 0.79 BCHE (0.36) BCHEACHEIDO1TDO2PRCP
SCHEMBL11391882 0.78 HTR2C (0.46) HTR2C
SCHEMBL30567955 0.78 HTR2C (0.46) HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137443-B Fluorene derivative, photopolymerization initiator containing same, and photoresist composition 克美 2021-06-08 CN disclosed
CN-107266334-B Fluorene compound, photopolymerization initiator containing the fluorene compound, and photosensitive composition containing the photopolymerization initiator 大东凯米克斯株式会社 2020-04-24 CN disclosed
EP-2913323-B1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR TOKYO OHKA KOGYO CO LTD (JP) 2018-09-12 EP disclosed
CN-107266334-A Fluorenes based compound, the Photoepolymerizationinitiater initiater containing the fluorenes based compound and the photo-sensitive composition containing the Photoepolymerizationinitiater initiater 大东凯米克斯株式会社 2017-10-20 CN disclosed
US-9684238-B2 Fluorene-type compound, photopolymerization initiator comprising said fluorene-type compound, and photosensitive composition containing said photopolymerization initiator TOKYO OHKA KOGYO CO., LTD. (JP) 2017-06-20 US disclosed
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR DAITO CHEMIX CORPORATION (JP) 2015-09-17 US disclosed
EP-2913323-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR Daito Chemix Corporation (JP) 2015-09-02 EP disclosed
CN-104684888-A Fluorene compound, photopolymerization initiator containing the fluorene compound, and photosensitive composition containing the photopolymerization initiator DAITO CHEMIX CORP 2015-06-03 CN disclosed
EP-0627440-B1 Metallocenes containing 9-substituted fluorenyl compounds and use of the metallocenes PHILLIPS PETROLEUM CO (US) 1999-08-18 EP disclosed
US-5610247-A Unbridged metallocenes of 9-substituted fluorenyl compounds and use thereof PHILLIPS PETROLEUM COMPANY (US) 1997-03-11 US disclosed
EP-0627440-A1 9-Substituted fluorenyl compounds and the preparation and use of metallocenes thereof PHILLIPS PETROLEUM COMPANY (US) 1994-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259321-A1 FLUORENE-TYPE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING SAID FLUORENE-TYPE COMPOUND, AND PHOTOSENSITIVE COMPOSITION CONTAINING SAID PHOTOPOLYMERIZATION INITIATOR AFF1, AFF2, FTO BCHE 4445/4885ACHE 2988/4885IDO1 521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.