Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704622 | 0.80 | BCHE (0.52) | IDO1TDO2BCHEACHEPRCP | |
| SCHEMBL8416138 | 0.80 | BCHE (0.52) | IDO1TDO2BCHEACHEPRCP | |
| SCHEMBL2806911 | 0.79 | NOS2 (0.36) | PRCPNOS2HTR2CHTR2AHTR2B | |
| SCHEMBL28225513 | 0.78 | BCHE (0.48) | IDO1TDO2BCHEACHEPRCP | |
| Hydrochloric Acid SCHEMBL8853642 | 0.76 | IDO1 (0.33) | IDO1TDO2BCHEACHEPRCP | |
| SCHEMBL28142477 | 0.74 | BCHE (0.44) | IDO1TDO2BCHEACHEPRCP | |
| SCHEMBL29988938 | 0.71 | ALDH1A1 (0.41) | IDO1TDO2BCHEACHEPRCP | |
| SCHEMBL7873616 | 0.70 | MYC (0.40) | ACHEHTR2CHTR2AHTR2BMYC | |
| SCHEMBL28946001 | 0.69 | SLC18A3 (0.44) | IDO1TDO2BCHEACHESIGMAR1 | |
| Biphenyl SCHEMBL9937258 | 0.68 | HTR2C (0.58) | PRCPDDB1CRBNHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627440-B1 | Metallocenes containing 9-substituted fluorenyl compounds and use of the metallocenes | PHILLIPS PETROLEUM CO (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5610247-A | Unbridged metallocenes of 9-substituted fluorenyl compounds and use thereof | PHILLIPS PETROLEUM COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0627440-A1 | 9-Substituted fluorenyl compounds and the preparation and use of metallocenes thereof | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-07 | — | — | EP | disclosed |