Ethylene Glycol

Ethylene Glycol

SCHEMBL8416280

C=C.C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCC1(OC2(CCCCCCCC)CCCCC2)CCCCC1.OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.36
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
CETP P11597 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1509039 1.00 LMNA (0.37) LMNAMEN1KMT2AALDH1A1HSD17B10
Ethylene Glycol SCHEMBL7118182 0.98 LMNA (0.38) LMNAMEN1KMT2AALDH1A1HSD17B10
Ethylene Glycol SCHEMBL5667972 0.98 LMNA (0.38) LMNAMEN1KMT2AALDH1A1HSD17B10
Ethylene Glycol SCHEMBL28069638 0.91 ALDH1A1 (0.33) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL956338 0.91 TSHR (0.35) MEN1KMT2ATSHRCYP4F2CYP4A11
SCHEMBL2496312 0.89 CETP (0.32) MEN1KMT2ATSHRSIRT2THRB
SCHEMBL790521 0.82 MEN1 (0.32) MEN1KMT2ACETP
SCHEMBL7118184 0.81 MEN1 (0.40) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL5667974 0.81 MEN1 (0.40) LMNAMEN1KMT2AALDH1A1HSD17B10
SCHEMBL6930926 0.80 TSHR (0.40) ALDH1A1TSHRSIRT2THRBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US claimed
US-5335373-A Protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-08-09 US claimed
EP-0934374-A2 NANOSTRUCTURED AQUEOUS FUELS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1999-08-11 EP disclosed
WO-1998018884-A2 NANOSTRUCTURED AQUEOUS FUELS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1998-05-07 WO disclosed
EP-0738391-A1 RADIAL FLOW ASSAY INTRACEL CORPORATION (US) 1996-10-23 EP disclosed
WO-1995018970-A1 RADIAL FLOW ASSAY INTRACEL CORPORATION (US) 1995-07-13 WO disclosed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US disclosed
US-5335373-A Protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-08-09 US disclosed