Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745995 | 0.85 | — | — | |
| SCHEMBL20519604 | 0.80 | — | — | |
| SCHEMBL1886149 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL1886148 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL10277 | 0.76 | — | — | |
| SCHEMBL23706944 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL6427158 | 0.71 | — | — | |
| Bicarbonate SCHEMBL15387390 | 0.70 | TSHR (0.50) | — | |
| Bicarbonate SCHEMBL9052387 | 0.70 | — | — | |
| Bicarbonate SCHEMBL31414980 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311974-B1 | PROCESS FOR PRODUCING (1S,2R)-2-CHLORO-2-FLUOROCYCLOPROPANECARBOXYLIC ACID | SUMITOMO CHEMICAL CO (JP) | 2012-12-19 | — | — | EP | claimed |
| EP-0743299-B1 | Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts | BAYER AG (DE) | 1999-09-15 | — | — | EP | claimed |
| EP-0726244-B1 | Process for producing 2-fluorocyclopropanecarboxylic acid | SUMITOMO CHEMICAL CO (JP) | 1998-08-12 | — | — | EP | claimed |
| EP-0755913-A1 | Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives | BAYER AG (DE) | 1997-01-29 | — | — | EP | claimed |
| EP-0743299-A1 | Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts and the chemical compound 2-fluorocyclopropylisocyanate | BAYER AG (DE) | 1996-11-20 | — | — | EP | claimed |
| EP-0436348-B1 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LTD (GB) | 1996-11-13 | — | — | EP | claimed |
| EP-3284739-A1 | SUBSTITUTED (HET) ARYL COMPOUNDS AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-02-21 | — | — | EP | disclosed |
| EP-0743299-B1 | Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts | BAYER AG (DE) | 1999-09-15 | — | — | EP | disclosed |
| EP-0726244-B1 | Process for producing 2-fluorocyclopropanecarboxylic acid | SUMITOMO CHEMICAL CO (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0755913-A1 | Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| EP-0755913-A1 | Process for preparing of 2,4-dibromo-4- and -3-fluorobutanoic acid as well as their derivatives | BAYER AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| EP-0743299-A1 | Process for the preparation of 2-fluorocyclopropylamine sulfonic acid salts and the chemical compound 2-fluorocyclopropylisocyanate | BAYER AG (DE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0726244-A1 | Process for producing 2-fluorocyclopropanecarboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0533013-B1 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| EP-0533013-A2 | Process for the production of 1-fluor-cyclopropane-1-carboxylic acid | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |