Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.65 |
| ▸ | ICMT | O60725 | 2/20 | 0.64 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 5/20 | 0.54 |
| ▸ | CNR2 | P34972 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840780 | 0.91 | CREBBP (0.62) | CDC25AICMTCREBBPL3MBTL1CNR1 | |
| SCHEMBL9038902 | 0.90 | CDC25A (0.56) | CDC25AICMTCREBBPL3MBTL1CNR1 | |
| SCHEMBL15747750 | 0.88 | CDC25A (0.67) | CDC25AICMTCNR1CNR2KDM4E | |
| SCHEMBL21245271 | 0.88 | ICMT (0.62) | CDC25AICMTCREBBPL3MBTL1CNR1 | |
| SCHEMBL18171795 | 0.85 | ALDH1A1 (0.66) | CREBBPL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL21535335 | 0.85 | CDC25A (0.73) | CDC25AICMTCNR1CNR2 | |
| SCHEMBL21245248 | 0.84 | CDC25A (0.56) | CDC25AICMTCREBBPL3MBTL1CNR1 | |
| SCHEMBL15747729 | 0.84 | CDC25A (0.90) | CDC25AICMTCNR1CNR2KDM4E | |
| SCHEMBL17102877 | 0.84 | CDC25A (0.75) | CDC25AICMTCNR1CNR2 | |
| SCHEMBL15747719 | 0.84 | CDC25A (0.75) | CDC25AICMTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |