Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | ICMT | O60725 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416334 | 0.90 | CDC25A (0.65) | CDC25ACREBBPICMTL3MBTL1MCL1 | |
| SCHEMBL28840780 | 0.89 | CREBBP (0.62) | CDC25ACREBBPICMTL3MBTL1MCL1 | |
| SCHEMBL21245271 | 0.86 | ICMT (0.62) | CDC25ACREBBPICMTL3MBTL1MCL1 | |
| SCHEMBL18171795 | 0.83 | ALDH1A1 (0.66) | CREBBPL3MBTL1LMNAALOX5ALDH1A1 | |
| SCHEMBL21245248 | 0.82 | CDC25A (0.56) | CDC25ACREBBPICMTL3MBTL1MCL1 | |
| SCHEMBL4208833 | 0.80 | L3MBTL1 (0.63) | CREBBPL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL8172186 | 0.80 | POLB (0.53) | CDC25AICMTL3MBTL1MCL1LMNA | |
| SCHEMBL28836439 | 0.80 | CDC25A (0.51) | CDC25ACREBBPICMTMCL1CNR1 | |
| SCHEMBL8181059 | 0.80 | CHRNB2 (0.58) | CREBBPL3MBTL1LMNAALOX5ALDH1A1 | |
| SCHEMBL8175090 | 0.79 | FNTA (0.57) | CREBBPL3MBTL1LMNAALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-B1 | Hexitol derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5053408-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |