Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MYLK | Q15746 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413208 | 0.86 | HTR6 (0.54) | L3MBTL1MAPTGAAPKMKDM4E | |
| SCHEMBL7823473 | 0.85 | L3MBTL1 (0.69) | L3MBTL1MAPTGAAPKMKDM4E | |
| SCHEMBL7824466 | 0.80 | L3MBTL1 (0.53) | L3MBTL1PKMKDM4EALDH1A1NPSR1 | |
| SCHEMBL8413419 | 0.78 | HTR6 (0.51) | MAPTGAAKDM4EKMT2AHSD11B1 | |
| SCHEMBL7832815 | 0.73 | L3MBTL1 (0.74) | L3MBTL1MAPTKDM4EHTR6ALDH1A1 | |
| SCHEMBL2772290 | 0.73 | LMNA (0.52) | L3MBTL1MAPTGAAKDM4EKMT2A | |
| SCHEMBL8413230 | 0.72 | CES1 (0.44) | GAAPKMKMT2AHTR6ALDH1A1 | |
| SCHEMBL7836456 | 0.72 | MAPT (0.60) | L3MBTL1MAPTGAAPKMKDM4E | |
| SCHEMBL7825681 | 0.72 | HTR6 (0.57) | L3MBTL1MAPTGAAPKMKDM4E | |
| Hydrochloric Acid SCHEMBL8056250 | 0.72 | L3MBTL1 (0.72) | L3MBTL1MAPTKDM4EHTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939451-A | INDOL-4-YL-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-17 | — | — | US | disclosed |
| US-5932599-A | 4-AMINO-N-(PYRIDINYL-4-YL)-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-03 | — | — | US | disclosed |