SCHEMBL8416376

SCHEMBL8416376

C/C(=C\C(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.32
CYP2C9 P11712 1/20 0.31
PTGS1 P23219 1/20 0.30
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2216095 1.00 DGAT1 (0.32) DGAT1CYP2C9PTGS1AKR1C3
SCHEMBL29092146 0.82 DGAT1 (0.32) DGAT1
SCHEMBL10295313 0.81 DGAT1 (0.34) DGAT1
SCHEMBL10295467 0.81 DGAT1 (0.34) DGAT1
SCHEMBL29874055 0.79 DGAT1 (0.33) DGAT1
SCHEMBL29109730 0.78 DGAT1 (0.39) DGAT1
SCHEMBL812341 0.78 ALOX15 (0.39) DGAT1
SCHEMBL28778066 0.77
SCHEMBL22615671 0.77 LMNA (0.31)
SCHEMBL22615673 0.77 LMNA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841380-B1 Method of making polymeric binders and use thereof in antifouling paints WITCO GMBH (DE) 1999-08-25 EP disclosed
EP-0841380-A1 Method of making polymeric binders and use thereof in antifouling paints Witco GmbH (DE) 1998-05-13 EP disclosed