Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180234 | 0.80 | CYP2C19 (0.38) | LMNACHRM2CHRM1CHRM3CYP2C19 | |
| SCHEMBL6180751 | 0.80 | CYP2C19 (0.38) | LMNACHRM2CHRM1CHRM3CYP2C19 | |
| SCHEMBL5705548 | 0.78 | OPRM1 (0.34) | SIGMAR1LMNARIPK1CHRM2CHRM4 | |
| SCHEMBL5705361 | 0.78 | OPRM1 (0.34) | SIGMAR1LMNARIPK1CHRM2CHRM4 | |
| SCHEMBL5705358 | 0.76 | CYP2C19 (0.35) | LMNACYP2C19HIF1ATAAR1ESR1 | |
| SCHEMBL3280082 | 0.75 | CYP2C19 (0.42) | SIGMAR1LMNARIPK1CHRM2CHRM4 | |
| SCHEMBL5705546 | 0.74 | CYP2C19 (0.36) | LMNACYP2C19HIF1AALDH1A1TAAR1 | |
| SCHEMBL5093688 | 0.73 | SIGMAR1 (0.59) | SIGMAR1LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL5091772 | 0.73 | SIGMAR1 (0.59) | SIGMAR1LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL3280880 | 0.72 | CYP2C19 (0.43) | SIGMAR1LMNARIPK1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872148-A | BRONCHODILATOR AGENTS AND ANALGESICS | UNIVERSITY OF CONNECTICUT (US) | 1999-02-16 | — | — | US | disclosed |
| US-5440052-A | Compositions useful as a cannabinoid receptor probe | UNIVERSITY OF CONNECTICUT (US) | 1995-08-08 | — | — | US | disclosed |