Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419532 | 0.81 | PLK1 (0.53) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL11121066 | 0.80 | KDM4E (0.47) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL7267342 | 0.80 | KDM4E (0.47) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL13570608 | 0.78 | TDP1 (0.49) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL7517030 | 0.74 | CDC25B (0.46) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL8419535 | 0.74 | KDM4E (0.52) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL4614497 | 0.73 | AAK1 (0.50) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL9643299 | 0.73 | AAK1 (0.50) | KDM4ECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL13570366 | 0.71 | GPR6 (0.49) | TSHR | |
| SCHEMBL8397188 | 0.70 | CTSC (0.49) | CYP3A4CYP2D6CYP1A2CYP2C19HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791071-B1 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS INC (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0791071-A1 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS, INC. (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5571684-A | SOLID PHASE CONJUGATE | LITMUS CONCEPTS, INC. (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996015255-A2 | ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES | LITMUS CONCEPTS, INC. (US) | 1996-05-23 | — | — | WO | disclosed |