Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8416593

N.O=C(O)CS(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.65
PKM P14618 1/20 0.59
MMP2 P08253 2/20 0.56
MMP7 P09237 1/20 0.56
MMP14 P50281 1/20 0.56
CA1 P00915 6/20 0.49
CA2 P00918 6/20 0.49
MMP1 P03956 1/20 0.49
MMP9 P14780 1/20 0.49
MMP8 P22894 1/20 0.49
MMP13 P45452 1/20 0.49
CA9 Q16790 5/20 0.48
CA4 P22748 4/20 0.48
CA12 O43570 4/20 0.48
CA14 Q9ULX7 4/20 0.48
CA3 P07451 3/20 0.48
CA6 P23280 3/20 0.48
CA5A P35218 3/20 0.48
CA7 P43166 3/20 0.48
CA13 Q8N1Q1 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415518 0.98 HSD11B1 (0.67) HSD11B1PKMMMP2MMP7MMP14
Guanidine SCHEMBL8415495 0.90 HSD11B1 (0.58) HSD11B1PKMMMP2MMP7MMP14
SCHEMBL10991739 0.82 PKM (0.63) HSD11B1PKMMMP2CA1CA2
SCHEMBL7861808 0.81 HTT (0.57) HSD11B1PKMMMP2CA1CA2
SCHEMBL28538245 0.80 HSD11B1 (0.91) HSD11B1PKMCA1CA2CA9
SCHEMBL3166376 0.79 HSD11B1 (0.50) HSD11B1PKMMMP2CA1CA2
SCHEMBL6908652 0.79 HSD11B1 (1.00) HSD11B1PKMCA1CA2CA9
Tetramethylammonium Ion SCHEMBL8416583 0.78 PKM (0.58) HSD11B1PKMMMP2CA1CA2
Tetramethylammonium Ion SCHEMBL8418460 0.78 PKM (0.58) HSD11B1PKMMMP2CA1CA2
SCHEMBL17550644 0.78 POLB (0.60) HSD11B1PKMMMP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605285-B1 Tetra-alkylammonium phenylsulfonylacetate thermal-dye-bleach agents MINNESOTA MINING & MFG (US) 1999-09-08 EP disclosed
EP-0605286-B1 Thermal-dye-bleach construction MINNESOTA MINING & MFG (US) 1998-06-24 EP disclosed
EP-0659581-B1 Stabilized thermal-dye-bleach constructions MINNESOTA MINING & MFG (US) 1997-10-15 EP disclosed
EP-0659581-A2 Stabilized thermal-dye-bleach constructions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-28 EP disclosed
US-5395747-A Polylactones as stabilizers in antihalation systems where an anion is thermally generated to decolor dyes formed by scattered light MINNESOTA MINING & MANUFACTURING COMPANY (US) 1995-03-07 US disclosed
US-5384237-A Quaternary-ammonium phenylsulfonylacetate thermal-dye-bleach agents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-01-24 US disclosed
EP-0605285-A1 Tetra-alkylammonium phenylsulfonylacetate thermal-dye-bleach agents MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-07-06 EP disclosed
EP-0605286-A1 Thermal-dye-bleach construction MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-07-06 EP disclosed
US-5324627-A Thermal carbanion generating agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-28 US disclosed
US-5314795-A Thermal-dye-bleach construction comprising a polymethine dye and a thermal carbanion-generating agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-24 US disclosed