Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418751 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDTDP1ADAMTS5 | |
| SCHEMBL8358555 | 0.79 | KMT2A (0.64) | ALDH1A1HPGDRAB9ASMN1; SMN2CA1 | |
| SCHEMBL22495484 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KDM4ERAB9ASMN1; SMN2CA1 | |
| Naphthyloxyacetic Acid SCHEMBL120838 | 0.76 | KDM4E (1.00) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| Naphthyloxyacetic Acid SCHEMBL29364154 | 0.76 | KDM4E (1.00) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| SCHEMBL10736563 | 0.76 | MAPK1 (0.63) | ALDH1A1KDM4EHPGDTDP1MAPK1 | |
| Naphthyloxyacetic Acid SCHEMBL15201763 | 0.75 | KDM4E (0.96) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| Naphthyloxyacetic Acid SCHEMBL6820182 | 0.75 | KDM4E (0.96) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| Naphthyloxyacetic Acid SCHEMBL8441282 | 0.75 | KDM4E (0.96) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| SCHEMBL8420406 | 0.74 | KDM4E (0.51) | ALDH1A1KDM4EHPGDTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |