Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418428 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| SCHEMBL8416779 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| SCHEMBL8354886 | 0.80 | KMT2A (0.55) | ALDH1A1HPGDKMT2AMEN1TSHR | |
| SCHEMBL8420341 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| SCHEMBL8420212 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| SCHEMBL693383 | 0.73 | TDP1 (0.49) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| Naphthyloxyacetic Acid SCHEMBL120838 | 0.72 | KDM4E (1.00) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| Naphthyloxyacetic Acid SCHEMBL29364154 | 0.72 | KDM4E (1.00) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| SCHEMBL8207302 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4ETDP1KMT2A | |
| SCHEMBL27858373 | 0.71 | KMT2A (0.58) | ALDH1A1HPGDKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719760-B1 | Naphthalene derivatives and their use as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1999-09-22 | — | — | EP | claimed |
| EP-0719760-A1 | Naphthyloxyacetic acid derivatives and their use as PGW2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |