Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.39 |
| ▸ | TET3 | O43151 | 2/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125700 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| SCHEMBL8416906 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| Malic Acid SCHEMBL6863763 | 0.77 | SMN1; SMN2 (0.88) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| SCHEMBL19912995 | 0.76 | OR51E2 (0.36) | SMN1; SMN2SLC22A6GABRR1LMNATET2 | |
| Malic Acid SCHEMBL856 | 0.75 | — | — | |
| Malic Acid SCHEMBL14125844 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| Malic Acid SCHEMBL98496 | 0.75 | — | — | |
| Malic Acid SCHEMBL256122 | 0.75 | — | — | |
| Malic Acid SCHEMBL89131 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| Malic Acid SCHEMBL31673489 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0692539-B1 | Process for producing an optically active gamma-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO KK (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5643769-A | Process for producing an optically active γ-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0692539-A2 | Process for producing an optically active gamma-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-01-17 | — | — | EP | disclosed |