Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233277 | 0.85 | SMN1; SMN2 (0.70) | KMT2AMEN1MAPTHTTSMN1; SMN2 | |
| SCHEMBL28012109 | 0.82 | KMT2A (0.68) | KMT2AMEN1CYP3A4MAPTCYP2C19 | |
| SCHEMBL6779077 | 0.81 | KMT2A (0.70) | KMT2AMEN1MAPTHTTSMN1; SMN2 | |
| SCHEMBL4833664 | 0.80 | HTT (0.62) | KMT2AMEN1CYP3A4MAPTHTT | |
| SCHEMBL8870819 | 0.79 | RAB9A (0.64) | KMT2AMEN1CYP3A4MAPTCYP2C19 | |
| SCHEMBL6396133 | 0.78 | KMT2A (0.85) | KMT2AMEN1CYP3A4MAPTHTT | |
| SCHEMBL30205486 | 0.78 | ALOX5 (0.69) | KMT2AMEN1CYP3A4MAPTCYP2C19 | |
| SCHEMBL6476104 | 0.77 | MAPK14 (0.70) | KMT2AMEN1CYP3A4MAPTNPC1 | |
| SCHEMBL14075256 | 0.76 | KMT2A (0.62) | KMT2AMEN1CYP3A4MAPTCYP2C19 | |
| SCHEMBL6476512 | 0.76 | HTT (0.74) | KMT2ACYP3A4MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791004-B1 | ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 1999-09-08 | — | — | EP | disclosed |
| US-5773420-A | Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0791004-A1 | ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014325-A1 | ACYLATED BENZYLGLYCOSIDES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-17 | — | — | WO | disclosed |